Diners boost their moods with crisp-edged, saucy burgers at this spot in Little Italy and Rosedale. Both locations sling simple cheeseburgers, layered Happy Stacks and pastrami-topped behemoths until 1 a.m., Sunday to Wednesday, and 2 a.m., the rest of the week.

In Parkdale and the Entertainment District, night owls sate cravings at this casual spot until 3 a.m., Friday and Saturday. With a menu that pushes the boundaries — here burgers are topped with chicken tenders, fried eggs, grilled pineapple and other outré options — no whim is too weird.

Head to this local chain, with locations at Yonge & Eglinton, in Little Italy, and more, for top-notch burgers, available until late. Layered with cheese, lettuce, tomato and Rudy sauce, the Rudy is simply satisfying. Still, some nights demand the Big Rudy, a towering invention built from three slices of bun, two patties and all the fixings.

Join the throngs who wrap up a night in the Entertainment District nuzzling steamy, saucy smash burgers at this vibrant spot. Customize your order or opt for one of the team's best-sellers, like the Birria Burger, the Shroom or the Picante. With hours that stretch to 2 a.m., Thursday to Sunday, and midnight the rest of the week, you never have to head home hungry.

When you're hungry and the clock has yet to strike 1 a.m., head to this Koreatown burger joint for deeply comforting sustenance. Fatty and beefy, topped simply or gussied up with mushrooms, bacon and caramelized onions, the team's smash burgers tick all the boxes.

Beyond nostalgia, a menu of diner-style eats, retro vibes and late hours draw diners to this Etobicoke spot. Until 2 a.m., Sunday to Thursday, and 3 a.m., Friday and Saturday, step back in time with loaded banquet burgers and double burgers, creamy milkshakes or the team’s famed grape soda.

Start or end your day at the Annex location of this chain, where gourmet burgers are available until 3 a.m., Sunday to Thursday, and 4 a.m., the rest of the week. Ground in-house, prime beef morphs into a solid selection of creatively topped classic and signature burgers.

Prices might be the only things that have changed since this Scarborough spot opened in 1967. Settle into the vintage space, until 1 a.m., or 3 a.m., Friday and Saturday, for simple, flame-licked burgers garnished with all the basics.

Even when Kensington Market quiets down, this spot can be relied on for fat burgers that satisfy. Crowded until midnight, and 3 a.m., Friday and Saturday, you might have to chill on the curb as you make one of the team’s hefty, gourmet two-handers — from the Notorious B.L.T. to the Holy Cheesus — disappear.